Tests for Efficacy Evaluation of CHOLLEY Phytocell Eye Contour Cream
FIRST TEST
The potential for eye (ocular) irritation of the product was analyzed. Based on an advanced in vitro methodology, this test reliably determines the irritancy potential of substance on ocular tissue.
Ocular Irritation Score | Classification |
0.0 – 12.5 | Minimally Irritant |
12.5 – 30.0 | Mildly Irritant |
30.0 – 51.0 | Moderately Irritant |
> 51.0 | Severely Irritant |
SECOND TEST
The cytotoxicity (toxic effect on cells) of the product was analyzed based on the ISO 10993-5:2009 in vitro method.
THIRD TEST
The test for product’s efficacy consisted of two separate tests to determine:
- Its regenerative power on blood vessels
- Its anti-inflammatory capacity to reduce puffines

SCIENTIFIC & DERMATOLOGICAL TEST RESULTS
Very strong increase of protein synthesis by as much as over 200%
Remarkable reduction of inflammatory agents – Interleukin 8 (IL8) and 6 (IL6) – by as much as 72% and 60% respectively in 8 weeks.
The maximum ocular irritation score of the Product was determined to be 4.8, which places it solidly in the safest classification. The skin is perfectly healthy.
No presence of potential cytotoxicity; the product is considered safe for application on skin cells.
* The study of this product was conducted by an independent laboratory to verify the anti-bags (puffiness) efficacy through the evaluation of its regenerating activity on human endothelial cells, and the evaluation of the anti-inflammatory action. Moreover, the evaluation of its cytotoxic potential was conducted, as well as the evaluation of the potential to cause ocular irritation.
TEST CONCLUSIONS
“CHOLLEY Phytocell Eye Contour Cream is considered an Excellent Product that prevents and “cures” the formation of under eye bags, puffiness, and wrinkles by strengthening the microcirculation and very strongly increasing the protein synthesis of the eye contour area”

SUPER PREMIUM EYE CONTOUR CREAM WITH EXCLUSIVE IC-RAMP® Technology

3-FUNCTIONS-ALL-IN-ONE PRODUCT:
Exceptional Anti-Wrinkles, Anti-Puffiness, and Anti Dark Circles.
15 ml – Ref. 1005V
CHOLLEY PHYTOCELL Eye Contour Cream, is a very effective and complete cream, especially formulated with our exclusive IC-RAMP® Technology, for problems of wrinkles, swelling, and dark circles. It is rich in Swiss phyto stem cell extracts, phytobiological actives, emollients, and hydrating factors.
Dermatologically and clinically tested.
Discover the exclusive features of IC-RAMP® Technology
BENEFITS
- Reduces the depth of wrinkles
- Diminishes the visibility of dark circles
- Increases the firmness and smoothness of the eye contour area
RECOMMENDED USE
CHOLLEY PHYTOCELL Eye Contour Cream, is exclusively for use on the skin of the periorbital (eye contour) and temple regions. It helps keep the skin smooth, firm, elastic, and wrinkle-free. The product is excellent for men and women of all ages. It holds back wrinkles, diminishes the visibility of dark circles, and reduces the puffiness of the eye contour area.
SKIN TYPES
For all skin types.
SPECIAL INGREDIENT: SYMPHYTUM STEM CELL EXTRACT
CHOLLEY PHYTOCELL Eye Contour Cream uses the stem cell extract of Symphytum obtained from Symphytum officinale, one of the oldest known medicinal plants with healing, anti-inflammatory, and soothing properties. Tests with tissues extracted from elderly subjects, have proven to be particularly notable, for building a thicker and smoother epidermis, with a higher content of hyaluronic acid.
CHOLLEY PHYTOCELL Eye Contour Cream also reduces congestion by improving the skin’s capillary circulation, which helps eliminate excess fluids. As a result, puffiness and under-eye dark circles diminish significantly in size and visibility.

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