What is IC-RAMP® Technology?

Swiss Stem Cells Cream & Serum - CHOLLEY

IC-RAMP® stands for Inter-Cellular Regenerative, Relay, Resonance and Amplification.

IC-RAMP® Technology  is at the forefront of research and development of stem cells cosmetics in Switzerland.

It is the driving technology behind the highly advanced CHOLLEY PHYTOCELL® PRODUCTS, which are designed as superbly effective skin care solutions for specific needs.

The combination of IC-RAMP® Technology with extracts of special stem cells such as the Alpine Rose, Argan, Vitis Vinifera, Lepidium Sativum Sprout and Uttwiler Spätlauber, delivers innovative and advanced stem cells cosmetics with outstanding effects and immediate results on your skin.  This technology represented the new frontier of CHOLLEY Anti-Aging and Skin Regenerating Products.

Inter- Cellular, Regenerative, Relay, Resonance, and Amplification

Inter-Cellular = A communication between epidermal and fibroblast cells

Regeneration = An easy regeneration of the extra-cellular matrix (ECM)

Relay = The signal communication

Resonance = The activation of fibroblasts

Amplification = A more efficient regeneration process that amplifies effects on skin

How It Works?

To understand how IC-RAMP works, you must first understand how the skin regenerates. When something happens, like a cut, the skin undergoes a regeneration process starting with the dermis. The dermis is where most aging tends to occur. Inside is the power to create Connective Tissue Growth Factor (or CTGF), which binds with fibroblasts to create new biological support structures within the skin like collagen, elastin, and hyaluronic acid.


Skin cells are in constant communication with one another. For instance, when the skin is cut, cells at all layers (epidermis, dermis, and hypodermis) get involved in preventing infection and healing the damage. Inter-cellular communication also involves regenerative processes.

As an example, exfoliation of dead epidermal cells triggers the production of new cells at the basal (germinating) layer of the skin


IC-RAMP® Technology  takes advantage of the same mechanism that the skin uses to heal itself after a cut or an abrasion.

IC-RAMP® Technology  utilizes inter-cellular communication to regenerate the skin. Based on the latest innovations in Swiss biotechnology, IC-RAMP® takes advantage of the capacity of special phyto stem cells  to trigger the release of Connective Tissue Growth Factor (CTGF) by the keratinocytes of the epidermis.

It reaches deep into the dermis layer to boost the production of a new connective tissue by fibroblast cells.


The dermis layer is where the most notable signs of aging – lines and wrinkles– develop as skin matures.

CTGF (Connective Tissue Growth Factor)  binds with special receptors on fibroblasts to set off the production of new collagen, elastin, and hyaluronic acid, which constitute the extra-cellular matrix (ECM) or the biological support structure of the skin.

This amplification of the skin regeneration process represents the driving force of IC-RAMP® Technology  in CHOLLEY PHYTOCELL PRODUCTS. 

If you want more technical information on our products:


Leave a comment